Nice. Looks a lot tidier than the last one of yours that I saw.
Some observations: You can probably shrink your buffs a little more. It's not really critical to have them dominate so much screen space. Maybe move them directly below the minimap? You'll free up a bit of centre screen real estate that way. Action bar blocks tend to be a little less intuitive for associated keybindings. That having been said, I use them too. Intuitive layouts are much less important if you're the only person that's ever going to use them. One other thing I suggest to a lot of people is to get rid of bag/keyring buttons altogether. Shift-B (or whatever else you want to bind) will open all your bags, and how often do you really need to look at your keys?